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- Tel: 858.663.9055
- Email: info@nsjbio.com
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BIRC4 is a member of a family of proteins which inhibit apoptosis through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2. Similar to API1, BIRC4 inhibits apoptosis induced by menadione, a potent inducer of free radicals, and ICE. BIRC4 also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7.
Titration of the XIAP antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 1-30 from the human protein was used as the immunogen for this XIAP antibody.
Aliquot the XIAP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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