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- Tel: 858.663.9055
- Email: info@nsjbio.com
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XDH belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The enzyme is a homodimer. This protein can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.
The stated application concentrations are suggested starting points. Titration of the XDH antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 206-234 from the human protein was used as the immunogen for the XDH antibody.
Aliquot the XDH antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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