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- Email: info@nsjbio.com
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The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
Titration of the XCR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 305-333 from human Lymphotactin Receptor was used as the immunogen for this XCR1 antibody.
Aliquot the XCR1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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