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Home >> Antibodies >> VAV2 Antibody (N-Terminal Region)

VAV2 Antibody (N-Terminal Region) (F54106)

  Catalog No Formulation Size Price (USD)  
Image F54106-0.2ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.2 ml 399
Image
F54106-0.05ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.05 ml 185
Bulk quote request
Western blot testing of VAV2 antibody at 1:2000: Lane 1) human HeLa, 2) MCF7 and 3) SH-SY5Y cell lysate. Predicted molecular weight ~100 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P52735
Applications Western Blot : 1:2000
Limitations This VAV2 antibody is available for research use only.
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Description

Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity). [UniProt]

Application Notes

The stated application concentrations are suggested starting points. Titration of the VAV2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 123--157 from human VAV2 was used as the immunogen for the VAV2 antibody.

Storage

Aliquot the VAV2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Cross
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