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Home >> Antibodies >> Tyrosinase Antibody / TYR

Tyrosinase Antibody / TYR [clone AAHE-20] (RQ5433)

  Catalog No Formulation Size Price (USD)  
Image RQ5433 Antibody in PBS with 0.02% sodium azide and 50% glycerol 100 ul 429
Microvalidated Rab Mono Image
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Western blot testing of human melanoma lysate with Tyrosinase antibody. Predicted molecular weight: 60-84 kDa depending on level of glycosylation.
Availability 1-2 weeks
Species Reactivity Human
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name AAHE-20
Purity Affinity purified
UniProt P14679
Applications Western blot : 1:500-1:2000
Limitations This Tyrosinase antibody is available for research use only.
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Description

The enzyme encoded by the TYR gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. [RefSeq]

Application Notes

Optimal dilution of the Tyrosinase antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human Tyrosinase / TYR was used as the immunogen for the Tyrosinase antibody.

Storage

Store the Tyrosinase antibody at -20oC.

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