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The tropomyosins are a family of actin filament binding proteins. These proteins were first isolated from skeletal muscle, but later identified in many nonmuscle tissues. Tropomyosins are ubiquitous proteins of 35 to 45 kD associated with the actin filaments of myofibrils and stress fibers. Vertebrates have at least 4 different tropomyosin genes; in humans, they are named TPM1, TPM2, TPM3, and TPM4. Tropomyosins expressed as different isoforms in muscle and non-muscle cells.
The stated application concentrations are suggested starting amounts. Titration of the Tropomyosin antibody, 36kD may be required due to differences in protocols and secondary/substrate sensitivity.
Chicken gizzard tropomyosin was used as the immunogen for this Tropomyosin antibody, 36kD.
After reconstitution, the Tropomyosin antibody, 36kD can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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