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Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking via its interaction with MAP6. May act by inhibiting retrograde transport of lysosomes along dendrites. Required for dendrite branching. [UniProt]
The stated application concentrations are suggested starting points. Titration of the TMEM106B antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 218-252 from human TMEM106B was used as the immunogen for the TMEM106B antibody.
Aliquot the TMEM106B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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