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Home >> Antibodies >> Thbd Antibody / Thrombomodulin

Thbd Antibody / Thrombomodulin [clone 28T28] (RQ8267)

  Catalog No Formulation Size Price (USD)  
Image RQ8267 Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA 100 ul 429
Microvalidated Recrabbitmono
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Western blot testing of mouse lung tissue lysate with Thbd antibody. Expected molecular weight ~60/100 kDa (unmodified/glycosylated).
Availability 1-3 business days
Species Reactivity Mouse, Rat
Format Purified
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name 28T28
Purity Affinity chromatography
UniProt P15306
Applications Western blot : 1:500-1:2000
Limitations This Thbd antibody is available for research use only.
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Description

Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. [UniProt]

Application Notes

Optimal dilution of the Thbd antibody should be determined by the researcher.

Immunogen

A synthetic peptide derived from human Thrombomodulin was used as the immunogen for the Thbd antibody.

Storage

Store the Thbd antibody at -20oC.

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