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Home >> Antibodies >> SUMO-2 Antibody

SUMO-2 Antibody (F42016)

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  Catalog No Formulation Size Price (USD)  
Image F42016-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
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F42016-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot analysis of SUMO-2 antibody and 293 cell lysate. Observed molecular weight: 12-15 kDa.
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Western blot analysis of SUMO-2 antibody and 293 cell lysate. Observed molecular weight: 12-15 kDa.
Western blot analysis of SUMO-2 antibody and 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (2) with the SUMO2 gene.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt P61956
Applications Western blot : 1:1000
Limitations This SUMO-2 antibody is available for research use only.
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Description

SUMO2 and SUMO3 are members of the SUMO (small ubiquitin-like modifier) protein family. This protein family functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. In vertebrates, three members of the SUMO family have been described, SUMO 1 and the functionally distinct homologues SUMO 2 and SUMO 3. SUMO modification sites present in the N terminal regions of SUMO 2 and SUMO 3 are utilized by SAE1/SAE2 (SUMO E1) and Ubc9 (SUMO E2) to form polymeric chains of SUMO 2 and SUMO 3 on protein substrates, a property not shared by SUMO 1.

Application Notes

Titration of the SUMO-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This SUMO-2 antibody was produced from rabbits immunized with a KLH conjugated synthetic peptide from the human protein.

Storage

Aliquot the SUMO-2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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