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Home >> Antibodies >> STAT6 Antibody

STAT6 Antibody (RQ7207)

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  Catalog No Formulation Size Price (USD)  
Image RQ7207 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Flow cytometry testing of human U937 cells with STAT6 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= STAT6 antibody.
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Flow cytometry testing of human U937 cells with STAT6 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= STAT6 antibody.
Western blot testing of human 1) HeLa, 2) 293T, 3) HepG2, 4) Jurkat and 5) Raji cell lysate with STAT6 antibody. Predicted molecular weight ~94 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt P42226
Applications Western blot : 0.5-1ug/ml
Flow cytometry : 1-3ug/million cells
Direct ELISA : 0.1-0.5ug/ml
Limitations This STAT6 antibody is available for research use only.
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Description

STAT6 is a human gene. The protein encoded by this gene is a member of the STAT family of transcription factors. The gene spans 19 kb and contains 23 exons. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2), expression of cell surface markers, and class switch of immunoglobulins.

Application Notes

Optimal dilution of the STAT6 antibody should be determined by the researcher.

Immunogen

Recombinant human protein (amino acids E13-Q810) was used as the immunogen for the STAT6 antibody.

Storage

After reconstitution, the STAT6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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