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- Email: info@nsjbio.com
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SOX7 belongs to SOX gene family and member proteins are transcription factors with critical roles in the regulation of diverse developmental processes. In cotransfected 293 cells, SOX7 reduced Wnt/beta-catenin stimulated transcription. SOX7 is a potent activator of FGF3 transcription. It not only plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium but also blocks further differentiation into blood precursors. And it may be required for the survival of both hematopoietic and endothelial precursors during specification.
The stated application concentrations are suggested starting amounts. Titration of the SOX7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
An amino acid sequence from the C-terminus of human SOX7 (LISVLADATATYYNSYSVS) was used as the immunogen for this SOX7 antibody (100% homologous in human, mouse and rat).
After reconstitution, the SOX7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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