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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Nuclear receptor coactivator NCOA62/SNW1 (also called Nuclear Protein SkiP, SKIIP, Ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.
Optimal dilution of the SNW1 antibody should be determined by the researcher.
A recombinant fragment of human SNW1 protein was used as the immunogen for the SNW1 antibody.
Aliquot the SNW1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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