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Home >> Antibodies >> Snurportin 1 Antibody / SNUPN

Snurportin 1 Antibody / SNUPN (RQ7741)

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  Catalog No Formulation Size Price (USD)  
Image RQ7741 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Immunofluorescent staining of FFPE human U-87 MG cells with Snurportin 1 antibody (red) and DAPI nuclear stain (blue). HIER: steam section in pH6 citrate buffer for 20 min.
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Immunofluorescent staining of FFPE human U-87 MG cells with Snurportin 1 antibody (red) and DAPI nuclear stain (blue). HIER: steam section in pH6 citrate buffer for 20 min.
Western blot testing of 1) human HeLa, 2) human ThP-1, 3) rat testis, 4) rat brain, 5) mouse testis and 6) mouse brain tissue lysate with Snurportin 1 antibody. Predicted molecular weight ~41 kDa.
Flow cytometry testing of human JK cells with Snurportin 1 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Snurportin 1 antibody.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt O95149
Localization Nuclear, cytoplasmic
Applications Western blot : 0.5-1ug/ml
Immunofluorescence : 5ug/ml
Flow cytometry : 1-3ug/million cells
Direct ELISA : 0.1-0.5ug/ml
Limitations This Snurportin 1 antibody is available for research use only.
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Description

Snurportin1 is a protein that in humans is encoded by the SNUPN gene. The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.

Application Notes

Optimal dilution of the Snurportin 1 antibody should be determined by the researcher.

Immunogen

E. coli-derived recombinant human protein (amino acids M1-N360) was used as the immunogen for the Snurportin 1 antibody.

Storage

After reconstitution, the Snurportin 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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