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Home >> Antibodies >> S100P Antibody

S100P Antibody [clone S100P/7373] (V5046)

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  Catalog No Formulation Size Price (USD)  
Image V5046-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V5046-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V5046SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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Western blot testing of human SK-BR-3 cell lysate with S100P antibody (clone S100P/7373). Predicted molecular weight ~10 kDa.
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Western blot testing of human SK-BR-3 cell lysate with S100P antibody (clone S100P/7373). Predicted molecular weight ~10 kDa.
IHC staining of FFPE human lung cancer with S100P antibody (clone S100P/7373). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human placental tissue with S100P antibody (clone S100P/7373). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human placenta with S100P antibody (clone S100P/7373). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human kidney with S100P antibody (clone S100P/7373). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free S100P antibody (clone S100P/7373) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2b, kappa
Clone Name S100P/7373
Purity Protein A/G affinity
UniProt P25815
Localization Nucleus, Cytoplasm
Applications Western blot : 1-2ug/ml
Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Limitations This S100P antibody is available for research use only.
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Description

S100P is a 95-amino-acid protein and a member of the S100 family. S100P has been shown to mediate tumor growth, metastasis and invasion through the binding of Ca2+ ions, receptor for advanced glycation end products, cytoskeletal protein ezrin, calcyclin-binding protein/Siah-1-interacting protein and cathepsin D. S100P highly expressed in human placenta, gastrointestinal tract, and esophageal mucosa, but always negative in pancreas and liver. Overexpression of S100P has been detected in several cancers such as breast, colon, prostate, pancreatic and lung carcinomas, and the protein has been functionally implicated in carcinogenic processes. S100P could potentially serve as diagnostic marker, prognostic/predictive indicator and therapy target for different carcinomas.

Application Notes

Optimal dilution of the S100P antibody should be determined by the researcher.

Immunogen

A recombinant partial protein sequence (within amino acids 1-95) from the human protein was used as the immunogen for the S100P antibody.

Storage

Aliquot the S100P antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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