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Home >> Antibodies >> Recombinant Lambda Antibody

Recombinant Lambda Antibody [clone LLC/3778R] (V7879)

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  Catalog No Formulation Size Price (USD)  
Image V7879-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V7879-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V7879SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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IHC staining of FFPE human spleen with recombinant Lambda antibody (clone LLC/3778R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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IHC staining of FFPE human spleen with recombinant Lambda antibody (clone LLC/3778R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human spleen with recombinant Lambda antibody (clone LLC/3778R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free recombinant Lambda antibody (clone LLC/3778R) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name LLC/3778R
Purity Protein A affinity chromatography
UniProt P01701 , P01842
Localization Cell surface, cytoplasmic, secreted
Applications Immunohistochemistry (FFPE) : 0.1-0.2ug/ml
Limitations This recombinant Lambda antibody is available for research use only.
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Description

This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Application Notes

Optimal dilution of the recombinant Lambda antibody should be determined by the researcher.

Immunogen

Recombinant full-length human IGL protein was used as the immunogen for the recombinant Lambda antibody.

Storage

Store the recombinant Lambda antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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