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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC, and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.
The stated application concentrations are suggested starting points. Titration of the Rac GTPase-activating protein 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 23-50 from the human protein was used as the immunogen for the Rac GTPase-activating protein 1 antibody.
Aliquot the Rac GTPase-activating protein 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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