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Home >> Antibodies >> Prothrombin Antibody / Thrombin / Coagulation Factor II / F2

Prothrombin Antibody / Thrombin / Coagulation Factor II / F2 (R31170)

  Catalog No Formulation Size Price (USD)  
Image R31170 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of Prothrombin antbody and rat testis lysate; Predicted molecular weight: 70 kDa, but may be observed at higher molecular weights due to glycosylation.
Availability 1-3 business days
Species Reactivity Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
UniProt P18292
Applications Western blot : 0.5-1ug/ml
Limitations This Prothrombin antibody is available for research use only.
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Description

F2 (Coagulation Factor II), also known as prothrombin and thrombin, is a serine protease that in humans is encoded by the F2 gene. The activated thrombin enzyme plays an important role in hemostasis and thrombosis: it converts fibrinogen to fibrin for blood clot formation, stimulates platelet aggregation, and activates coagulation factors V, VIII (F8), and XIII (F13A1). Thrombin also inhibits coagulation by Activating protein C.

Application Notes

Titration of the Prothrombin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

Amino acids 600-612 (THVFRLKRWMQKV-rat) were used as the immunogen for this Prothrombin antibody.

Storage

After reconstitution, the Prothrombin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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