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- Tel: 858.663.9055
- Email: info@nsjbio.com
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The progesterone receptor (PR) is an intracellular steroid receptor that specially binds progesterone in humans. It is encoded by a single PGR gene residing on chromosome 11q22. The PR gene uses separate promoters and translational start sites to produce 2 isoforms, PRA and PRB, which are identical except for an additional 165 amino acids present only in the N terminus of PRB. It can be observed in human breast tissues. The proteins function as dimeric molecules in nuclei to regulate the transcription of target genes in a ligand-responsive manner.
The stated application concentrations are suggested starting amounts. Titration of the Progesterone Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Human partial recombinant protein (AA 595-933) was used as the immunogen for this Progesterone Receptor antibody.
After reconstitution, the Progesterone Receptor antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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