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Protein inhibitor of activated STAT (PIAS), also known as E3 SUMO-protein ligase PIAS, is a protein that regulates transcription in mammals. PIAS proteins act as transcriptional co-regulators with at least 60 different proteins in order to either activate or repress transcription. The transcription factors STAT, NF-κB, p73, and p53 are among the many proteins that PIAS interacts with. PIAS proteins have potential applications in cancer treatment and prevention. They may also play an important role in regulating immune system responses. [Wiki]
Optimal dilution of the PIAS1/2/3 antibody should be determined by the researcher.
A synthetic peptide specific to human PIAS 1 & 2 & 3 was used as the immunogen for the PIAS1/2/3 antibody.
Store the PIAS1/2/3 antibody at -20oC.
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