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The VIM gene encodes a type III intermediate filament protein. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton. The encoded protein is responsible for maintaining cell shape and integrity of the cytoplasm, and stabilizing cytoskeletal interactions. This protein is involved in neuritogenesis and cholesterol transport and functions as an organizer of a number of other critical proteins involved in cell attachment, migration, and signaling. [RefSeq]
Optimal dilution of the phospho-Vimentin antibody (pS72) should be determined by the researcher.
A synthetic peptide specific to human Vimentin (surrounding phosphorylated serine 72) was used as the immunogen for the phospho-Vimentin antibody.
Store the phospho-Vimentin antibody (pS72) at -20oC.
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