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- Email: info@nsjbio.com
The protein encoded by the PDGFRB gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. [RefSeq]
Optimal dilution of the phospho-PDGFRB antibody (pY740) should be determined by the researcher.
A synthetic peptide specific to PDGF Receptor beta (surrounding phosphorylated Y740) was used as the immunogen for the phospho-PDGFRB antibody.
Store the phospho-PDGFRB antibody (pY740) at -20oC.
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