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Home >> Antibodies >> PDK4 Antibody

PDK4 Antibody [clone 345CT19.6.2] (F40320)

  Catalog No Formulation Size Price (USD)  
Image F40320-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F40320-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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PDK4 antibody western blot analysis in K562 lysate. Expected/observed molecular weight ~46 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1
Clone Name 345CT19.6.2
Purity Purified
UniProt Q16654
Applications Western blot : 1:100
Limitations This PDK4 antibody is available for research use only.
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Description

This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.

Application Notes

Titration of the PDK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A purified His-tagged recombinant protein fragment was used to produced this monoclonal PDK4 antibody.

Storage

Aliquot the PDK4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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