- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
P4HTM Antibody / HIF Prolyl Hydroxylases / HIFPH4 [clone 28P22] (RQ8306)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
RQ8306 | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA | 100 ul | 429 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | 28P22 |
| Purity | Affinity chromatography |
| UniProt | Q9NXG6 |
| Applications | Western blot : 1:500-1:2000 |
| Limitations | This P4HTM antibody is available for research use only. |
|
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|
Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. [UniProt]
Optimal dilution of the P4HTM antibody should be determined by the researcher.
A synthetic peptide derived from human HIF Prolyl Hydroxylases was used as the immunogen for the P4HTM antibody.
Store the P4HTM antibody at -20oC.
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