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Home >> Antibodies >> Opticin Antibody / OPTC

Opticin Antibody / OPTC (RQ7921)

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  Catalog No Formulation Size Price (USD)  
Image RQ7921 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of 1) human ARPE-19 and 2) monkey RF/6A cell lysate with Opticin antibody. Predicted molecular weight ~37 kDa but may be observed at a higher molecular weight due to glycosylation.
Western blot testing of 1) human ARPE-19 and 2) monkey RF/6A cell lysate with Opticin antibody. Predicted molecular weight ~37 kDa but may be observed at a higher molecular weight due to glycosylation.
Availability 1-3 business days
Species Reactivity Human, Monkey
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q9UBM4
Applications Western blot : 0.5-1ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This Opticin antibody is available for research use only.
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Description

Opticin is a protein that in humans is encoded by the OPTC gene. Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are typically associated with the extracellular matrix. Opticin is present in significant quantities in the vitreous of the eye and also localizes to the cornea, iris, ciliary body, optic nerve, choroid, retina, and fetal liver. Opticin may noncovalently bind collagen fibrils and regulate fibril morphology, spacing, and organization. The opticin gene is mapped to a region of chromosome 1 that is associated with the inherited eye diseases age-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa (AXPC1).

Application Notes

Optimal dilution of the Opticin antibody should be determined by the researcher.

Immunogen

E. coli-derived recombinant human protein (amino acids E32-Q250) was used as the immunogen for the Opticin antibody.

Storage

After reconstitution, the Opticin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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