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- Email: info@nsjbio.com
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Op18 (for oncoprotein 18, also designated stathmin, prosolin or metablastin) is a conserved, Tubulin-associated, intracellular phosphoprotein. Many different phosphorylated forms of Op18 are observed, and it is expressed as two different isoforms. Op18 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phophorylation, for a variety of cell signaling pathways and is involved in both mitosis and differentiation. Op18 is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.
Optimal dilution of the Op18 antibody should be determined by the researcher.
A recombinant fragment of human Stathmin 1 protein was used as the immunogen for the Op18 antibody.
Aliquot the Op18 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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