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Home >> Antibodies >> NUDCD1 Antibody

NUDCD1 Antibody (RQ8413)

  Catalog No Formulation Size Price (USD)  
Image RQ8413 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q96RS6
Applications Western blot : 0.5-1ug/ml
Immunohistochemistry (FFPE) : 2-5ug/ml
Immunofluorescence : 5ug/ml
ELISA : 0.1-0.5ug/ml
Limitations This NUDCD1 antibody is available for research use only.
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Description

NudC domain containing 1 (NudCD1), also known as CML66 or OVA66, is a protein initially identified as overexpressed in patients with chronic myelogenous leukemia. The mRNA of NudCD1 is expressed in heart and testis of normal tissues, and is overexpressed in several cancers. The expression level of the protein correlates with tumoral phenotype, possibly interacting upstream of the Insulin Growth Factor - 1 Receptor (IGF-1R). The gene encoding the NudCD1 protein consists of 12 exons that can be alternative spliced, leading to the expression of three different isoforms. These isoforms possess a common region of 492 amino acids in their C-terminus region and have an isoform specific N-terminus.

Application Notes

Optimal dilution of the NUDCD1 antibody should be determined by the researcher.

Immunogen

An E.coli-derived human recombinant protein (Q72-K578) was used as the immunogen for the NUDCD1 antibody.

Storage

After reconstitution, the NUDCD1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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