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- Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Nebulin is a giant protein component of the cytoskeletal matrix that coexists with the thick and thin filaments within the sarcomeres of skeletal muscle. In most vertebrates, nebulin accounts for 3 to 4% of the total myofibrillar protein and its size varies from 600 to 800 kD in a manner that is tissue-, species-, and developmental stage-specific. The nebulin gene contains 183 exons in a 249-kb genomic region. Nebulin is mapped to chromosome 2. Nebulin is a giant filamentous protein specific for vertebrate skeletal muscles. Mutations in the nebulin gene associated with autosomal recessive nemaline myopathy.
The stated application concentrations are suggested starting amounts. Titration of the Nebulin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Chicken breast nebulin was used as the immunogen for this Nebulin antibody.
After reconstitution, the Nebulin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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