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Home >> Antibodies >> MUC20 Antibody

MUC20 Antibody (F40163)

  Catalog No Formulation Size Price (USD)  
Image F40163-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F40163-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot analysis of MUC20 antibody and 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MUC20 gene (2).
Confocal immunofluorescent analysis of MUC20 antibody with WiDr cells followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used as a nuclear counterstain (blue).
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt Q8N307
Applications Western blot : 1:1000
Immunofluorescence : 1:10-1:50
Limitations This MUC20 antibody is available for research use only.
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  • Applications : WB, IHC, IF, FACS, ELISA
    Reactivity : Human

Description

MUC20 may regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression. [UniProt]

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the MUC20 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 61-90 from the human protein was used as the immunogen for this MUC20 antibody.

Storage

Aliquot the MUC20 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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