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Home >> Antibodies >> Msln Antibody / Mesothelin

Msln Antibody / Mesothelin (RQ8301)

  Catalog No Formulation Size Price (USD)  
Image RQ8301 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of mouse heart tissue lysate with Msln antibody. Predicted molecular weight ~69 kDa.
Availability 1-3 business days
Species Reactivity Mouse
Format Antigen affinity purified
Clonality Polyclonal
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q61468
Applications Western blot : 0.5-1ug/ml
ELISA : 0.1-0.5ug/ml
Limitations This Msln antibody is available for research use only.
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Description

Mesothelin, also known as MSLN or MPF, is a protein that in humans is encoded by the MSLN gene. This gene is mapped to 16p13.3. This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas.

Application Notes

Optimal dilution of the Msln antibody should be determined by the researcher.

Immunogen

An E.coli-derived mouse recombinant protein (Q44-K497) was used as the immunogen for the Msln antibody.

Storage

After reconstitution, the Msln antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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