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Home >> Antibodies >> MMP1 Antibody

MMP1 Antibody (F41755)

  Catalog No Formulation Size Price (USD)  
Image F41755-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F41755-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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MMP1 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human esophageal carcinoma
Confocal immunofluorescent analysis of MMP1 antibody with MDA-MB231 cells followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used as a nuclear counterstain (blue).
MMP1 antibody western blot analysis in MDA-MB231 lysate. Expected/observed molecular weight ~54 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P03956
Applications Western blot : 1:1000
IHC (Paraffin) : 1:50-1:100
Immunofluorescence : 1:10-1:50
Limitations This MMP1 antibody is available for research use only.
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Description

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.

Application Notes

Titration of the MMP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 317-347 from the human protein was used as the immunogen for this MMP1 antibody.

Storage

Aliquot the MMP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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