- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
MLH1 Antibody (F41625)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F41625-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
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F41625-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity |
| UniProt | P40692 |
| Applications | Western blot : 1:1000 Flow Cytometry : 1:10-1:50 |
| Limitations | This MLH1 antibody is available for research use only. |
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This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.
Titration of the MLH1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 452-480 from the human protein was used as the immunogen for this MLH1 antibody.
Aliquot the MLH1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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