• Tel: 858.663.9055
  • SeparatorEmail: info@nsjbio.com
  • Tel: 858.663.9055
  • Email: info@nsjbio.com
Order
Home >> Antibodies >> MeCP2 Antibody

MeCP2 Antibody (F48101)

NSJ bio Image Pdf Image
  Catalog No Formulation Size Price (USD)  
Image F48101-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F48101-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
Bulk quote request
Western blot testing of MeCP2 antibody at 1:2000 dilution + mouse brain lysate; Observed molecular weight: ~55 kDa and ~75 kDa.
›
Western blot testing of MeCP2 antibody at 1:2000 dilution + mouse brain lysate; Observed molecular weight: ~55 kDa and ~75 kDa.
Western blot testing of MeCP2 antibody at 1:2000 dilution. Lane 1: SH-SY5Y lysate; 2: Jurkat; 3: A431; 4: HepG2; 5: NIH3T3; Observed molecular weight: ~55 kDa and ~75 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q95LG8
Applications Western blot : 1:1000
Limitations This MeCP2 antibody is available for research use only.
Review this product on BioCompare and get a $20 Amazon gift card

Related Products

  • Applications : WB
    Reactivity : Human
  • Applications : WB, IHC, FACS, ELISA
    Reactivity : Human
    Pred. Reactivity : Mouse, Rat, Primate
  • Applications : WB, FACS, ELISA
    Reactivity : Human
    Pred. Reactivity : Primate
  • Applications : WB, FACS, ELISA
    Reactivity : Human
    Pred. Reactivity : Mouse
  • Applications : DB, ELISA
    Reactivity : Human
    Pred. Reactivity : Mouse, Primate, Rat
  • Applications : IHC-P, WB
    Reactivity : Human, Mouse, Rat

Description

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of some cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. [RefSeq]

Application Notes

Titration of the MeCP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 400-428 from the macfa protein was used as the immunogen for this MeCP2 antibody.

Storage

Aliquot the MeCP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Related Products

   1.   View all MeCP2 antibodies

Cross
Bulk Quote Request Form
Name*:
Organization*:
Email*:
Phone Number*:
Catalog No.*:
Comments and Specifics(amount, formulation, etc.)*:
Validation code: Captchapackage Image


Can't read the image? click here to refresh.
    *required field

Your bulk quote request has been submitted successfully!

Please contact us if you have any questions.