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Home >> Antibodies >> MCP2 Antibody / CCL8

MCP2 Antibody / CCL8 [clone CCL8/3311] (V9514)

  Catalog No Formulation Size Price (USD)  
Image V9514-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V9514-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V9514SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated
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Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using MCP2 antibody (clone CCL8/3311). These results demonstrate the foremost specificity of the CCL8/3311 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
SDS-PAGE analysis of purified, BSA-free MCP2 antibody (clone CCL8/3311) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name CCL8/3311
Purity Protein A/G affinity
UniProt P80075
Localization Secreted
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This MCP2 antibody is available for research use only.
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Description

This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.

Application Notes

Optimal dilution of the MCP2 antibody should be determined by the researcher.

Immunogen

A portin of amino acids 1-100 from the human protein was used as the immunogen for the MCP2 antibody.

Storage

Aliquot the MCP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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