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Home >> Antibodies >> Max-binding protein MNT Antibody / MNT

Max-binding protein MNT Antibody / MNT (RQ8302)

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  Catalog No Formulation Size Price (USD)  
Image RQ8302 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Immunofluorescent staining of FFPE human HeLa cells with Max-binding protein MNT antibody (red) and Beta Tubulin mAb (green). HIER: steam section in pH6 citrate buffer for 20 min.
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Immunofluorescent staining of FFPE human HeLa cells with Max-binding protein MNT antibody (red) and Beta Tubulin mAb (green). HIER: steam section in pH6 citrate buffer for 20 min.
Western blot testing of human 1) HeLa and 2) A431 cell lysate with Max-binding protein MNT antibody. Predicted molecular weight ~62 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q99583
Localization Nuclear
Applications Western blot : 0.5-1ug/ml
Immunofluorescence : 5ug/ml
ELISA : 0.1-0.5ug/ml
Limitations This Max-binding protein MNT antibody is available for research use only.
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Description

MNT (Max-binding protein MNT) is a Max-binding protein that is encoded by the MNT gene The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.

Application Notes

Optimal dilution of the Max-binding protein MNT antibody should be determined by the researcher.

Immunogen

An E.coli-derived human recombinant protein (R222-A582) was used as the immunogen for the Max-binding protein MNT antibody.

Storage

After reconstitution, the Max-binding protein MNT antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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