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Home >> Antibodies >> MAVS Antibody / IPS-1

MAVS Antibody / IPS-1 (RQ6496)

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  Catalog No Formulation Size Price (USD)  
Image RQ6496 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Immunofluorescent staining of FFPE human Caco-2 cells with MAVS antibody (green) and DAPI nuclear stain (blue). HIER: steam section in pH6 citrate buffer for 20 min.
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Immunofluorescent staining of FFPE human Caco-2 cells with MAVS antibody (green) and DAPI nuclear stain (blue). HIER: steam section in pH6 citrate buffer for 20 min.
Western blot testing of human 1) HeLa and 2) Jurkat cell lysate with MAVS antibody. Expected molecular weight: 51-54 kDa (cleaved), 57 kDa (unmodified), 75 kDa (aggregated).
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q7Z434
Localization Cytoplasmic
Applications Western blot : 1-2ug/ml
Immunofluorescence : 5ug/ml
Limitations This MAVS antibody is available for research use only.
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Description

Mitochondrial antiviral-signaling protein (MAVS) is a protein that in humans is encoded by the MAVS gene. The protein is also known by the names VISA (virus-induced signaling adapter), IPS-1 and Cardif. This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity.

Application Notes

Optimal dilution of the MAVS antibody should be determined by the researcher.

Immunogen

Amino acids DEVASVYQSYQPRTSDRPPDPLE from the human protein were used as the immunogen for the MAVS antibody.

Storage

After reconstitution, the MAVS antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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