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Home >> Antibodies >> MARCHF2 Antibody

MARCHF2 Antibody (RQ8435)

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  Catalog No Formulation Size Price (USD)  
Image RQ8435 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q9P0N8
Applications Western blot : 0.5-1ug/ml
Immunofluorescence : 5ug/ml
ELISA : 0.1-0.5ug/ml
Limitations This MARCHF2 antibody is available for research use only.
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Description

MARCH2 is an E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC and CD86, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. MARCH2 may be involved in endosomal trafficking through interaction with STX6.

Application Notes

Optimal dilution of the MARCHF2 antibody should be determined by the researcher.

Immunogen

An E.coli-derived human recombinant protein (M1-V246) was used as the immunogen for the MARCHF2 antibody.

Storage

After reconstitution, the MARCHF2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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