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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Mammaglobin, 10 kDa, is a cytoplasmic protein, a mammary-specific member of the uteroglobin family. It is related to a family of epithelial secretory proteins that includes prostatein and Clara cell protein.Mammaglobin occurs in about 80% of breast carcinomas. The extend is generally larger than that of GCDFP-15. Up to 15% of nonbreast carcinomas (such as stomach, lung, colon, hepatobiliary, thyroid, ovarian, and urothelial carcinomas) have been reported positive, usually only focally. Mammaglobin is a sensitive and fairly specific marker for breast carcinoma. The panel should also include Gross cystic disease fluid protein-15 and Estrogen receptor alpha.
Optimal dilution of the Mammaglobin antibody should be determined by the researcher.
A recombinant fragment of human Mammaglobin/SCGB2A2 protein was used as the immunogen for the Mammaglobin antibody.
Aliquot the Mammaglobin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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