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- Email: info@nsjbio.com
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Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Stimulates axonal outgrowth and may be involved in brain development. Isoform 3 has a dominant negative effect on actin cytoskeletal changes.
Titration of the LIMK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 479-508 from the human protein was used as the immunogen for this LIMK1 antibody.
Aliquot the LIMK1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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