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Home >> Antibodies >> LIMK1 Antibody

LIMK1 Antibody [clone 175CT3.2.5] (F40237)

  Catalog No Formulation Size Price (USD)  
Image F40237-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F40237-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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LIMK1 antibody western blot analysis in mouse brain tissue lysate. Expected molecular weight ~72 kDa.
Availability 1-3 business days
Species Reactivity Mouse
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, k
Clone Name 175CT3.2.5
Purity Purified
UniProt P53667
Applications Western blot : 1:100-1:1000
Limitations This LIMK1 antibody is available for research use only.
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Description

Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Stimulates axonal outgrowth and may be involved in brain development. Isoform 3 has a dominant negative effect on actin cytoskeletal changes.

Application Notes

Titration of the LIMK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 479-508 from the human protein was used as the immunogen for this LIMK1 antibody.

Storage

Aliquot the LIMK1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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