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- Tel: 858.663.9055
- Email: info@nsjbio.com
Kv2.1 also called DRK1, is a protein that in humans is encoded by the KCNB1 gene. KCNB1 is found in cardiomyocytes, skeletal muscles, vascular smooth muscles, placental vasculature, retina, and pancreatic beta-cells. It can mediates the voltage-dependent potassium ion permeability of excitable membranes. KCNB1 represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume.
The stated application concentrations are suggested starting amounts. Titration of the Kv2.1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Human partial recombinant protein (AA 687-858) was used as the immunogen for this Kv2.1 antibody.
After reconstitution, the Kv2.1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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