- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Ku80 Antibody / XRCC5 [clone FAE-24] (RQ5399)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
RQ5399 | Antibody in PBS with 0.02% sodium azide and 50% glycerol | 100 ul | 429 |
|
| Availability | 1-2 weeks |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | FAE-24 |
| Purity | Affinity purified |
| UniProt | P13010 |
| Applications | Western blot : 1:5000-1:10000 |
| Limitations | This Ku80 antibody is available for research use only. |
|
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The protein encoded by the XRCC5 gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [RefSeq]
Optimal dilution of the Ku80 antibody should be determined by the researcher.
A synthetic peptide specific to human Ku80 / XRCC5 was used as the immunogen for the Ku80 antibody.
Store the Ku80 antibody at -20oC.
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