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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Irak4 is required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Phosphorylates IRAK1 (By similarity).
Titration of the Irak4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 422-449 from the mouse protein was used as the immunogen for this Irak4 antibody.
Aliquot the Irak4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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