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Home >> Antibodies >> IRAK4 Antibody

IRAK4 Antibody (F42537)

  Catalog No Formulation Size Price (USD)  
Image F42537-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F42537-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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IRAK4 antibody western blot analysis in NCI-H460 lysate. Predicted molecular weight 52/37 kDa (isoforms 1/2).
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse, Bovine
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q9NWZ3
Applications Western blot : 1:1000
Limitations This IRAK4 antibody is available for research use only.
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Description

This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

Application Notes

Titration of the IRAK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 25-52 from the human protein was used as the immunogen for this IRAK4 antibody.

Storage

Aliquot the IRAK4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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