- Tel: 858.663.9055
- Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Titration of the IRAK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 25-52 from the human protein was used as the immunogen for this IRAK4 antibody.
Aliquot the IRAK4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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