- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Interleukin-1 Receptor Antagonist Antibody / IL1RA / IL1RN [clone 12C13] (RQ6530)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
RQ6530 | 0.5mg/ml if reconstituted with 0.2ml sterile DI water | 100 ug | 429 |
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The interleukin-1 receptor antagonist (IL-1RA) is a protein that in humans is encoded by the IL1RN gene. The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
Optimal dilution of the Interleukin-1 Receptor Antagonist antibody should be determined by the researcher.
An E. coli-derived rat protein (amino acids H27-Q178) was used as the immunogen for the Interleukin-1 Receptor Antagonist antibody.
After reconstitution, the Interleukin-1 Receptor Antagonist antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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