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Home >> Antibodies >> IL10 Antibody

IL10 Antibody (RQ4550)

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  Catalog No Formulation Size Price (USD)  
Image RQ4550 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of 1) human U-87 MG, 2) rat testis, 3) mouse testis and 4) mouse SP20 lysate with IL10 antibody at 0.5ug/ml. Predicted molecular wieght ~20 kDa.
Western blot testing of 1) human U-87 MG, 2) rat testis, 3) mouse testis and 4) mouse SP20 lysate with IL10 antibody at 0.5ug/ml. Predicted molecular wieght ~20 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt P22301
Applications Western blot : 0.5-1ug/ml
Direct ELISA : 0.1-0.5ug/ml (human recombinant protein)
Limitations This IL10 antibody is available for research use only.
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Description

Interleukin-10 (IL-10 or IL10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine. In humans IL-10 is encoded by the IL10 gene. It is capable of inhibiting synthesis of pro-inflammatory cytokines like IFNg, IL-2, IL-3, TNFa and GM-CSF made by cells such as macrophages and regulatory T-cells.IL-10 also displays potent abilities to suppress the antigen presentation capacity of antigen presenting cells. Kim et al. (1992) showed that the mouse Il 10 gene contains 5 exons and spans about 5.2 kb of genomic DNA. Eskdale et al. (1997) mapped the IL10 gene to the junction between 1q31 and 1q32.

Application Notes

Optimal dilution of the IL10 antibody should be determined by the researcher.

Immunogen

Amino acids S19-N178 from the human protien were used as the immunogen for the IL10 antibody.

Storage

After reconstitution, the IL10 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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