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Home >> Antibodies >> IL-10RA Antibody / IL-10R1

IL-10RA Antibody / IL-10R1 [clone 1B1.3a] (V8346)

  Catalog No Formulation Size Price (USD)  
Image V8346-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V8346-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V8346SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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Availability 1-3 business days
Species Reactivity Mouse
Format Purified
Clonality Monoclonal (rat origin)
Isotype Rat IgG1, kappa
Clone Name 1B1.3a
Purity Protein G affinity chromatography
UniProt Q61727
Applications Flow cytometry : 1-2ug/10^6 cells
Limitations This IL-10RA antibody is available for research use only.
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Description

This monoclonal antibody recognizes Mouse Interleukin-10 receptor 1 (IL-10R1), a cell surface glycoprotein of approximately 110KDa. Its epitope is localized in the ligand-binding domain in the extracellular region of Mouse IL-10R1. This antibody blocks the binding of IL-10 to its receptor. IL-10R1 is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Binding of IL-10 to its receptor initiates JAK/STAT signaling that leads to B cell proliferation and inhibition of macrophage activation.

Application Notes

Optimal dilution of the IL-10RA antibody should be determined by the researcher.

Immunogen

Purified recombinant extracellular region of mouse IL10RA was used as the immunogen for the IL-10RA antibody.

Storage

Store the IL-10RA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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