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Home >> Antibodies >> IGFBP3 Antibody

IGFBP3 Antibody (F50624)

  Catalog No Formulation Size Price (USD)  
Image F50624-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F50624-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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IHC analysis of FFPE human hepatocarcinoma tissue stained with IGFBP3 antibody
Western blot analysis of IGFBP3 antibody and HepG2 lysate. The glycoprotein is visualized between 31~44 kDa.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Rat
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt P17936
Localization Secreted
Applications Western blot : 1:1000
IHC (Paraffin) : 1:10-1:50
Limitations This IGFBP3 antibody is available for research use only.
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Description

IGFBP3 is a member of the insulin-like growth factor binding protein (IGFBP) family with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors.

Application Notes

Titration of the IGFBP3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 163-193 from the human protein was used as the immunogen for this IGFBP3 antibody.

Storage

Aliquot the IGFBP3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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