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Home >> Antibodies >> HMGA2 Antibody

HMGA2 Antibody (F49146)

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  Catalog No Formulation Size Price (USD)  
Image F49146-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F49146-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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HMGA2 antibody western blot analysis in HepG2 lysate. Predicted molecular weight ~12kDa but routinely observed at ~18kDa.
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HMGA2 antibody western blot analysis in HepG2 lysate. Predicted molecular weight ~12kDa but routinely observed at ~18kDa.
HMGA2 antibody flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control (left histogram). FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P52926
Applications Western blot : 1:1000
Flow Cytometry : 1:10-1:50
Limitations This HMGA2 antibody is available for research use only.
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Description

This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Application Notes

Titration of the HMGA2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 64-92 from the human protein was used as the immunogen for this HMGA2 antibody.

Storage

Aliquot the HMGA2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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