- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
HLA-DRB1 Antibody (F54895)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F54895-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
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F54895-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity purified |
| UniProt | P04229 |
| Localization | Cytoplasmic, membranous |
| Applications | Western blot : 1:500-1:1000 Immunohistochemistry (FFPE) : 1:10-1:50 Flow cytometry : 1:10-1:50 (1x10e6 cells) |
| Limitations | This HLA-DRB1 antibody is available for research use only. |
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HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons.
The stated application concentrations are suggested starting points. Titration of the HLA-DRB1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 30-58 from the human protein was used as the immunogen for the HLA-DRB1 antibody.
Aliquot the HLA-DRB1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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