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Home >> Antibodies >> GSDMD Antibody / Gasdermin D

GSDMD Antibody / Gasdermin D [clone 3D5] (RQ7928)

  Catalog No Formulation Size Price (USD)  
Image RQ7928 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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IHC staining of FFPE human lymph node tissue with GSDMD antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human liver cancer tissue with GSDMD antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human esophagus tissue with GSDMD antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
Western blot testing of human 1) ThP-1, 2) SW620, 3) Jurkat, 4) U-87 MG and 5) PC-3 cell lysate with GSDMD antibody. Predicted molecular weight ~53 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2a
Clone Name 3D5
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt P57764
Localization Nucleus, cytoplasm, cell membrane, secreted
Applications Western blot : 0.5-1ug/ml
Immunohistochemistry (FFPE) : 2-5ug/ml
Limitations This GSDMD antibody is available for research use only.
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Description

Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described.

Application Notes

Optimal dilution of the GSDMD antibody should be determined by the researcher.

Immunogen

E. coli-derived recombinant human protein (amino acids M1-H484) was used as the immunogen for the GSDMD antibody.

Storage

After reconstitution, the GSDMD antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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