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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Alpha-galactosidase is a glycoside hydrolase enzyme that encoded by the GLA gene. This gene is a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.
Optimal dilution of the Gla antibody should be determined by the researcher.
Amino acids 218-275 (DIQYYCNHWRNFDDVYDSWESIKNILSWTVVYQKEIVEVA-mouse) were used as the immunogen for the Gla antibody.
After reconstitution, the Gla antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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